2008
Composite Porous Silicon-Crystalline Silicon Cantilevers for Enhanced Biosensing
STOLYAROVA, Sara, Cherian SUMAN, Roberto RAITERI, Jiří ŽERAVÍK, Petr SKLÁDAL et. al.Basic information
Original name
Composite Porous Silicon-Crystalline Silicon Cantilevers for Enhanced Biosensing
Name in Czech
Kompozitní kantilevry na bázi porézního křemíku a krystalického křemíku pro vylepšení biosensorů
Authors
STOLYAROVA, Sara (376 Israel), Cherian SUMAN (356 India), Roberto RAITERI (380 Italy), Jiří ŽERAVÍK (203 Czech Republic), Petr SKLÁDAL (203 Czech Republic, guarantor) and Yael NEMIROVSKY (376 Israel)
Edition
Sensors and Actuators B Chemical, Amsterdam (Holandsko), Elsevier, 2008, 0925-4005
Other information
Language
English
Type of outcome
Article in a journal
Field of Study
10600 1.6 Biological sciences
Country of publisher
Netherlands
Confidentiality degree
is not subject to a state or trade secret
Impact factor
Impact factor: 3.122
RIV identification code
RIV/00216224:14310/08:00025703
Organization unit
Faculty of Science
UT WoS
000256116100022
Keywords in English
Porous silicon; Microcantilever; Antibody; Silanization; Fluorescence label
Tags
International impact, Reviewed
Changed: 29/6/2009 16:24, prof. RNDr. Petr Skládal, CSc.
V originále
Cantilever transducers, which are recognized as a promising platform for the next generation of chemical and biological sensors, are currently under extensive research. Here we report composite porous silicon-crystalline silicon microcantilevers made of SOI wafers, where the porous silicon surface provides an excellent interface for immobilization of the biosensing layer. We start with crystalline silicon cantilevers fabricated from SOI wafers and we establish a surface layer of porous silicon on the cantilevers by vapor phase stain etching. The processed porous silicon does not introduce signi?cant static bending of the cantilevers indicating that it does not introduce signi?cant residual stress. It does provide an excellent biocompatible material for immobilization of a wide variety of chemical and biological materials, resulting in enhanced sensitivity as demonstrated on the covalently immobilized antibody binding its complementary antigen.
In Czech
Metodika modifikace povrchu porézního křemíku na bázi silanizace, vhodná pro imobilizaci protilátek na povrch kantilevrů - nanomechanických převodníků pro biosensory.
Links
LC06030, research and development project |
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MSM0021622413, plan (intention) |
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