J 2008

Composite Porous Silicon-Crystalline Silicon Cantilevers for Enhanced Biosensing

STOLYAROVA, Sara, Cherian SUMAN, Roberto RAITERI, Jiří ŽERAVÍK, Petr SKLÁDAL et. al.

Basic information

Original name

Composite Porous Silicon-Crystalline Silicon Cantilevers for Enhanced Biosensing

Name in Czech

Kompozitní kantilevry na bázi porézního křemíku a krystalického křemíku pro vylepšení biosensorů

Authors

STOLYAROVA, Sara (376 Israel), Cherian SUMAN (356 India), Roberto RAITERI (380 Italy), Jiří ŽERAVÍK (203 Czech Republic), Petr SKLÁDAL (203 Czech Republic, guarantor) and Yael NEMIROVSKY (376 Israel)

Edition

Sensors and Actuators B Chemical, Amsterdam (Holandsko), Elsevier, 2008, 0925-4005

Other information

Language

English

Type of outcome

Article in a journal

Field of Study

10600 1.6 Biological sciences

Country of publisher

Netherlands

Confidentiality degree

is not subject to a state or trade secret

Impact factor

Impact factor: 3.122

RIV identification code

RIV/00216224:14310/08:00025703

Organization unit

Faculty of Science

UT WoS

000256116100022

Keywords in English

Porous silicon; Microcantilever; Antibody; Silanization; Fluorescence label

Tags

International impact, Reviewed
Changed: 29/6/2009 16:24, prof. RNDr. Petr Skládal, CSc.

Abstract

V originále

Cantilever transducers, which are recognized as a promising platform for the next generation of chemical and biological sensors, are currently under extensive research. Here we report composite porous silicon-crystalline silicon microcantilevers made of SOI wafers, where the porous silicon surface provides an excellent interface for immobilization of the biosensing layer. We start with crystalline silicon cantilevers fabricated from SOI wafers and we establish a surface layer of porous silicon on the cantilevers by vapor phase stain etching. The processed porous silicon does not introduce signi?cant static bending of the cantilevers indicating that it does not introduce signi?cant residual stress. It does provide an excellent biocompatible material for immobilization of a wide variety of chemical and biological materials, resulting in enhanced sensitivity as demonstrated on the covalently immobilized antibody binding its complementary antigen.

In Czech

Metodika modifikace povrchu porézního křemíku na bázi silanizace, vhodná pro imobilizaci protilátek na povrch kantilevrů - nanomechanických převodníků pro biosensory.

Links

LC06030, research and development project
Name: Biomolekulární centrum
Investor: Ministry of Education, Youth and Sports of the CR, Biomolecular centre
MSM0021622413, plan (intention)
Name: Proteiny v metabolismu a při interakci organismů s prostředím
Investor: Ministry of Education, Youth and Sports of the CR, Proteins in metabolism and interaction of organisms with the environment